RAD-140 vs RAD-150: What's the Difference?

rad-140 vs rad-150

RAD-140 vs RAD-150: Everything you need to know

When it comes to Selective Androgen Receptor Modulators (SARMs), RAD-140 and RAD-150 are two compounds that often get compared. With claims that RAD-150 is a game changer, it's natural to wonder how it stacks up against its predecessor, RAD-140. 

In this article, we'll explore the key differences between RAD-140 and RAD-150, backed by factual data and anecdotal reports. 

So if you've been curious about these SARMs and their effects, keep reading to learn more about RAD-140 vs RAD-150.

Introduction to RAD-140 and RAD-150

RAD-140 and RAD-150 are both selective androgen receptor modulators (SARMs) that have gained popularity in the medical and fitness world.(1) These compounds are known for their ability to promote muscle growth and improve bone health.

It is essential to consider the potential risks and benefits of using RAD-140 or RAD-150 before incorporating them into your fitness or medical regimen.

Overview of RAD-140

RAD-140, also known as Testolone, is a selective androgen receptor modulator (SARM) that is known for its potential benefits in promoting lean muscle gain and enhancing athletic performance. It works by binding to androgen receptors in the body, stimulating muscle and bone growth without causing the undesirable side effects associated with traditional anabolic steroids.

RAD-140 is highly sought after by bodybuilders and athletes for its ability to promote muscle growth and improve physical performance. It has been shown to increase lean muscle mass, enhance strength gains, and improve endurance.

Additionally, RAD-140 has neuroprotective effects, meaning it may help protect brain cells and potentially improve cognitive function.(2)

This SARM has a unique advantage of selectively targeting androgen receptors in muscle and bone tissues, while sparing other organs and tissues in the body. This selective action contributes to its performance-enhancing effects without the negative side effects commonly associated with anabolic steroids.

Overall, RAD-140 offers significant potential for individuals looking to improve their physique, increase muscle mass, and enhance athletic performance. However, it is important to note that additional research is still needed to fully understand its long-term effects and any potential risks associated with its use. 

Overview of RAD-150

RAD-150, also known as TLB-150, is a selective androgen receptor modulator (SARM) that is gaining popularity in the medical and fitness world. It is known for its ability to promote muscle growth and improve bone density.

Unlike RAD-140, which primarily focuses on muscle wasting diseases and has strong anabolic effects, RAD-150's main benefit lies in its ability to increase muscle mass and improve bone health.(3)

The specific characteristics of RAD-150 make it an ideal option for individuals looking to enhance their physique and overall strength. It helps increase muscle density, promotes weight loss, and improves overall body composition.

However, it's important to note that RAD-150, like any other SARM, should be used responsibly and under the guidance of a healthcare professional. Each individual may respond differently to the compound, and it's essential to monitor any potential side effects.

Overall, RAD-150 offers a unique set of benefits, particularly in terms of muscle mass and bone density improvement.

RAD-140 vs. RAD-150 Effects and Benefits

When comparing the effects and benefits of RAD-140 and RAD-150, both compounds offer unique advantages for muscle growth, strength increase, and fat loss.

RAD-140 Effects and Benefits

RAD-140, also known as Testolone, is a selective androgen receptor modulator (SARM) that offers several specific effects and benefits.

  • Muscle Growth: One of the primary effects of RAD-140 is its ability to promote lean muscle mass. It helps increase muscle growth, allowing individuals to achieve a more defined and muscular physique. Additionally, RAD-140 has the ability to enhance endurance, allowing users to perform intense workouts for longer periods.
  • Fast Post-Workout Recovery: Another benefit of RAD-140 is its impact on recovery. It helps expedite the recovery process by reducing muscle damage and inflammation. This enables individuals to recover faster and get back to their training regime more quickly.
  • Minimal Side Effects: it comes to RAD-140 effects, it is important to note that it does not convert into estrogen, making it a suitable option for individuals concerned about potential estrogen-related side effects. RAD-140 also has a relatively low risk of causing liver toxicity compared to other performance-enhancing substances.

Overall, RAD-140 is a popular choice among athletes, bodybuilders, and fitness enthusiasts due to its ability to promote lean muscle mass, boost endurance, and aid in post-workout recovery.

RAD-150 Effects and Benefits

RAD-150, also known as TLB-150, is a selective androgen receptor modulator (SARM) that offers unique effects and benefits in the medical and fitness world. While RAD-140 primarily focuses on muscle growth and anabolic effects, RAD-150 offers a different set of advantages.

  • Improved Bone Health: One of the key benefits of RAD-150 is its positive impact on bone density. It helps promote bone health and strength, making it an ideal compound for individuals dealing with bone-related issues or those looking to improve their overall bone health.
  • Increased Muscle Density: RAD-150 can help individuals achieve and maintain a lean muscle mass. It aids in increasing muscle density, providing a more defined and sculpted appearance.
  • Weight Loss: Another advantage of RAD-150 is its potential for weight loss. By increasing muscle density and promoting fat loss, it can contribute to a more efficient metabolism and aid in achieving weight management goals.

While RAD-140 and RAD-150 have some overlapping effects, they each offer unique benefits to users. Understanding these distinctions helps individuals make informed decisions based on their specific goals and health considerations.

RAD-140 vs. RAD-150 Side Effects

When comparing the side effects of RAD-140 and RAD-150, it's important to note that these compounds are selective androgen receptor modulators (SARMs) and have similar mechanisms of action. However, there are some differences in the potential side effects:


  • Testosterone Suppression: RAD-140 has the potential to suppress natural testosterone production, leading to hormonal imbalances. This is easily mitigated with post-cycle therapy (PCT) to restore testosterone levels.
  • Liver Toxicity: While RAD-140 is considered safe, long-term, high-dose use may potentially cause liver toxicity. It's important to follow recommended dosage guidelines.
  • Mood Changes: RAD-140 may affect mood and mental health in some individuals. Mood swings, irritability, and aggression have been reported, although they are less common than with anabolic steroids.


  • Limited Research: RAD-150 is a relatively new SARM, and its side effects are not well-documented and are difficult to determine. However, as a popular SARM, it is likely to have similar side effects to RAD-140, such as testosterone suppression and potential liver toxicity.

It's also vital to adhere to recommended dosages and incorporate proper PCT (post-cycle therapy) measures to avoid and minimize side effects.

RAD-150 vs. RAD-140 Bodybuilding Results

When comparing the bodybuilding results of RAD-150 and RAD-140, it is important to understand that both compounds are selective androgen receptor modulators (SARMs) with anabolic effects, meaning they can promote muscle growth and increase strength.

RAD-140, also known as Testolone, is particularly effective for building lean muscle mass, improving endurance, and aiding in recovery after intense workouts. It can help users gain significant muscle size and strength while reducing body fat.

On the other hand, RAD-150, also known as TLB-150,(4) is known for its ability to increase muscle density and promote bone health. It can enhance muscle mass and improve overall physical performance. Additionally, RAD-150 has shown potential for weight loss benefits.

Both RAD-150 and RAD-140 can contribute to bodybuilding goals by supporting muscle growth, fat loss, and workout recovery. However, it is essential to consult with a healthcare professional or fitness expert before using any SARMs to ensure safety and effectiveness.

Please note that the information provided here is for informational purposes only and should not be medical or professional advice.

Similarities and Differences Between RAD-140 and RAD-150

When comparing RAD-140 and RAD-150, both are selective androgen receptor modulators (SARMs) that have gained popularity in the medical and fitness world for their potential benefits in muscle growth and bone health. However, there are key differences between the two compounds:


  • Both RAD-140 and RAD-150 are synthetic compounds that mimic the effects of testosterone.
  • They have been shown to increase muscle mass, strength, stamina, and endurance.
  • Both compounds can help reduce recovery time after intense workouts.
  • RAD-140 and RAD-150 are safe and effective, with no serious reported side effects.


  • RAD-140 is known as Testolone and has a reputation for producing the best dry gains in the industry. It is one of the stronger SARMs and requires post-cycle therapy (PCT).
  • RAD-150 is an iteration of RAD-140 with an added ester through esterification, making it slightly stronger than RAD-140.
  • RAD-150 has been reported to have a better taste than RAD-140, possibly due to the addition of the ester.
  • Users have reported more pronounced side effects with RAD-150, including hair shedding and higher aggression, compared to RAD-140.
  • RAD-140 has a recommended dosage of 10mg per day, while RAD-150 is slightly stronger and may require a lower dosage of 5mg per day.

While both RAD-140 and RAD-150 share some similarities in their effects and benefits, there are notable differences in terms of muscle growth, strength increase, fat loss, and bone health. 

Additionally, RAD-140 has been associated with some mild side effects such as testosterone suppression, while RAD-150 has not been reported to cause any significant side effects. When considering SARMs for bodybuilding, it's important to weigh the potential effectiveness and safety of each compound and consider individual health considerations.

Final Verdict

In comparing RAD-140 and RAD-150, it is important to consider the specific needs and goals of the individual. 

On the other hand, RAD-150, also known as TLB-150, focuses more on bone health and muscle density. It can help improve bone density and strength, making it beneficial for individuals with bone health issues. Additionally, RAD-150 may aid in weight loss efforts due to its impact on insulin sensitivity.

When deciding between RAD-140 and RAD-150, personal preference and health considerations should be taken into account. It is recommended to consult with a medical professional or fitness expert to determine the most suitable option based on individual needs and goals.


Can RAD-140 and RAD-150 be used by both men and women?

Yes, both RAD-140 and RAD-150 can be used by both men and women. However, it is important to note that these compounds are typically used by athletes and bodybuilders for performance enhancement and not recommended for recreational use.

How long does it take to see results with RAD-140 and RAD-150?

The timeframe for experiencing results will vary depending on individual factors, such as diet, exercise, and dosage. However, some users may start to notice improvements in muscle growth, strength, and fat loss within a few weeks of starting a cycle. The average half-life of RAD 140 is 20 hours, whilst the average half-life of RAD 150 is 48 hours.

Can RAD-140 and RAD-150 be stacked with other supplements?

Stacking RAD-140 and RAD-150 with other supplements is possible, but it is important to carefully research and understand the potential interactions and effects. Consulting with a healthcare professional or a knowledgeable trainer is recommended before incorporating supplements into a stack.

Are RAD-140 and RAD-150 legal to use?

The legal status of RAD-140 and RAD-150 may vary depending on the country or jurisdiction. It is important to research and comply with the laws and regulations in your specific location before purchasing or using these compounds.

Can RAD-140 and RAD-150 be used for medical purposes?

RAD-140 and RAD-150 are both selective androgen receptor modulators (SARMs) and have shown potential in research studies for certain medical conditions, such as muscle wasting diseases and bone health. However, they are still under investigation and not approved for medical use by regulatory bodies.

What is the recommended dosage for RAD-140 and RAD-150?

The recommended dosage for RAD-140 and RAD-150 may vary depending on factors such as experience level, goals, and tolerance. On average, the dosage RAD 140 and RAD 150 dosage is 10 mg per day, for up to 8 weeks. It is important to start with a low dosage and gradually increase as needed while closely monitoring for any potential side effects. Consulting with a healthcare professional is advised for personalized dosage recommendations.

Can RAD-140 and RAD-150 be used for weight loss?

Both RAD-140 and RAD-150 have been reported to have potential effects on fat loss, but it is important to remember that they are primarily used for performance enhancement and not as weight loss supplements. Proper diet, exercise, and healthy lifestyle choices are key for achieving sustainable weight loss.

  1. Rosen, J, and A Negro-Vilar. “Novel, non-steroidal, selective androgen receptor modulators (SARMs) with anabolic activity in bone and muscle and improved safety profile.” Journal of musculoskeletal & neuronal interactions vol. 2,3 (2002): 222-4.
  2. Jayaraman, Anusha et al. “Selective androgen receptor modulator RAD140 is neuroprotective in cultured neurons and kainate-lesioned male rats.” Endocrinology vol. 155,4 (2014): 1398-406. doi:10.1210/en.2013-1725
  3. Ross, S B. “Pharmacokinetics of haloalkylamines: cyclization and distribution in blood in vitro and in vivo.” The Journal of pharmacy and pharmacology vol. 27,5 (1975): 322-8. doi:10.1111/j.2042-7158.1975.tb09449.x
  4. Wadhwa, Vivek K et al. “Bicalutamide monotherapy preserves bone mineral density, muscle strength and has significant health-related quality of life benefits for osteoporotic men with prostate cancer.” BJU international vol. 107,12 (2011): 1923-9. doi:10.1111/j.1464-410X.2010.09726.x
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