SARMs vs. Prohormones: What's Better + Differences Explained

Losing fat and gaining that well-defined muscles are already a tough journey for most people. With enough discipline, one can still achieve their bodybuilding goals, but performance still plateaus at a certain point.

Pharmaceuticals are in the race of producing the right supplements that can expedite the process and can get you out of the training plateau when you need to. Such is the role of prohormones SARMs and similar types.

Although they serve the same purpose, SARMs and prohormones have performance-enhancing nature, but their mechanisms are entirely different.

This article will help you understand what are SARMs bodybuilding dosages, the differences between SARMs vs. prohormones, what they do to your body, and which one would work best on your physique and goals.

SARMs Overview

SARMs stands for Selective Androgen Receptor Modulators and are designed to treat specific health conditions, notably muscle wasting and bone wasting diseases, HIV/AIDS, and other chronic diseases.

sarms overview

Since SARMs were not developed for the muscle treatment of fit people, SARMs still remain as research chemicals used by bodybuilding communities.

Better hormone treatments were soon developed for the ailments SARMs were intended for. However, research formulas are still available, and it was only a matter of time before they were replicated for a different purpose.

While a prohormone goes through a two-step conversion to become a target hormone, a SARM has a more direct way of signaling and stimulating androgen receptors, which makes them similar to anabolic steroids. However, the potency of SARMs is noted to be weaker than that of prohormones.

In the ’90s, many, if not most of the bodybuilders used anabolic steroids to build on their muscles and cut all the fats they deem unnecessary.

Using steroids entailed many side effects like a higher risk of heart disease, liver failure, infertility, gynecomastia, and even aggressive behavior. Abuse can even lead to sudden death.

The steroids also work on androgen receptors in the body as SARMs do, but as its name suggests, SARMs are selective in targeting the body components they are intended for. It targets and interacts only with the androgen receptors of the muscle and bone tissues.

SARMs will not raid other parts of your body like the kidneys or the liver. Thus, you can enjoy the effects of muscle building without suffering the consequences of using steroids.

RELATED: SR9011 Review: SARM Benefits, Dosage & Side Effects


Those who use SARMs will get the following results:

  • Get lean muscle mass
  • Enhanced strength
  • Faster recovery
  • Help cut body fat
  • Unsuppressed natural testosterone levels
  • Non conversion into estrogen, thus saving users from gynecomastia or man boobs.
  • Mild

Side Effects

SARMs are popular for their mild nature as a selective androgen receptor. Used appropriately, one can enjoy its great rewards without repercussions.

sarms side effects

Some varieties are potent though it can become problematic when abused. Some of them are RAD-140, LGD-4033, and S23. The side effects may include the following.

  • Acne breakout
  • Oily skin
  • Increased bad cholesterol
  • Suppression

Suppose you’re looking into stacking SARMs with prohormones for better results. In that case, you have to undergo Post Cycle Therapy or PCT for SARMs to avoid suppression of natural testosterone and other hormones.

One supplement should be used at a time, and add the lowest effective dose of another SARMs or prohormones after a few cycles to advance the stack.

5 Most Popular SARMs

There are a few popular types available, but the most popular ones are the following:

  • MK-677
  • LGD-4033 – Ligandrol
  • MK-2866 – Ostarine
  • GSX-007 – Andarine
  • GW-501516 – Cardarine


Prohormones are prodrugs, which means they change into something else when ingested in the body.

After taking the chemical, which is considered a precursor to hormones, it is converted into anabolic hormones within the body, thanks to enzymes’ interaction.

As the levels of hormone increase, users will experience the anabolic effect within a shorter period. Effects include muscle growth, fat loss, increase in strength, and stamina.

An important thing with prohormones is that they show up on drug tests suggesting using anabolic steroids, so athletes may get under scrutiny for using this supplement.


  • Highly potent muscle mass gain
  • Powerful increase in strength
  • Muscle growth with less fat gain on a bulk
  • Cutting body fat
  • Improved sleep
  • Faster recovery
  • Increased appetite
  • Improved motivation and aggression in the gym

3 Most Popular Prohormones

  • Androsta-1-ene-3b-ol,17-one
  • 2,17a-dimethyl-5a-androsta-1-en-17b-ol-3-one
  • 2a, 3a epithio-17a-methyl-5a-androstan-17b-ol

Side Effects

The main difference between SARMs vs. prohormones is how they suppress natural testosterone levels and toxicity levels. This means using prohormones would require liver support.

The risk of experiencing the following side effects spikes when the dosage is increased, or cycles are lengthened more than necessary.

  • Acne breakout
  • Headaches
  • Dizziness
  • Water retention
  • Low libido
  • Mood swings
  • Suppression
  • Gynecomastia
  • High blood pressure
  • Hepatotoxicity

Users are usually advised to take it with other compounds such as Androtest to prevent suppression and an aromatase inhibitor like Arimistane.

Frequently Asked Questions (FAQ)

Your questions answered.

Are SARMs and Prohormones Safe?

Since SARMs are only available as research compounds and are not fit for human consumption, certain issues might be related to their consumption yet to be identified.

are sarms and prohormones safe

There is no anecdotal evidence yet that tells of any red flag. Until the regulating authorities clear the compounds, it is still good to not ignore the possibility of serious complications.

Users can experience the same effects with Prohormone as that of anabolic-androgenic steroids but to a milder degree. They affect several organs in the body and may have serious adverse effects, but they are still different and better than steroids.

The prohormones available today can be considered safe as long as they are taken within the recommended guidelines.

  1. Research and understand the compounds you are planning to use.
  2. Seek professional assistance when using.
  3. Use quality cycle support.
  4. Run a proper PCT after a cycle.
  5. Stay within the recommended cycle length.
  6. Don’t exceed the recommended dosages.
  7. Stay away from any alcohol.

It starts to get clear about why many people prefer SARMs. Prohormones are associated with several adverse reactions that may leave you questioning whether it is even beneficial to use them in the first place.

Are SARMs and Prohormones Legal?

SARMs are not legal to buy for human consumption, but you can have them as research compounds in the US and most of Europe. Check the specific regulations before buying them in your country.

As for the prohormones, regulations were put into check to alleviate the use of the old prohormones. Designer Steroid Control Act Is one of those that ban powerful prohormones. Today they are banned as Schedule III Drugs.

There are still several legal prohormones available, but they won’t give you the results you need and nowhere as powerful as the old prohormones we knew.


Pitting prohormones vs. SARMs and deciding which is best for one’s goals can be boiled down to how fast we want the results, the risks associated with the products, and the accessibility of the supplements.

Although prohormones can guarantee great gains, they come with a risk of side effects like liver toxicity. It would also require a proper PCT as it is highly suppressive of your hormones.

If you are looking into building that lean muscle, some recent posts or reviews would recommend SARMs because of the lower risk of side effects.

If we are just judging SARM vs. prohormone in terms of side effects and overall safety to users, SARMs come out on top.

SARMs may be slow-acting, but it will still give you the great results you need. It does not always require a PCT, depending on dosage and cycle length. There are barely any side effects unless one runs on a high dosage. It can also be stacked with any other supplements, while prohormones would present you with minimal options.

However, take note that neither SARMs nor prohormones that tell of anabolic steroid use are allowed in drug tested sports.

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