SR9009 vs SR9011: Which Exercise Enhancer is Best?

SR9009 vs SR9011: Everything you need to know

Have you been looking for an exercise enhancer that help you achieve your fitness goals? With the range of options available on the market, it is difficult to decide which one is the best fit for you. Two of the most widely known exercise enhancers are SR9009 and SR9011, both of which have been touted for their ability to improve endurance and strength. 

But, which one of them is the better choice? 

In this article, we will delve into the nuances of SR9009 vs SR9011 and help you determine the best exercise enhancer option to take your fitness journey to new heights!

Introduction to SR9009 and SR9011

SR9009 and SR9011 are two research chemicals commonly known as Stenabolic. They belong to a class of compounds called Rev-ErbA agonists.(1) These chemicals were initially developed for studying the circadian rhythm,(2) metabolism,(3) and endurance in preclinical models. SR9009 was the first compound of its kind to be discovered, while SR9011 followed shortly after.

While SR9009 primarily enhances endurance and regulates metabolism, SR9011 offers additional benefits for muscle growth. 

Overview of SR9009

SR9009, also known as Stenabolic, is a research chemical that falls under the class of Rev-ErbA agonist. It was developed by Professor Thomas Burris at The Scripps Research Institute as a means to study the body's circadian rhythm. However, it soon became apparent that SR9009 had a variety of potential applications, especially in the field of exercise enhancement.

One of the key properties of SR9009 is its ability to activate Rev-ErbA, a protein that plays a crucial role in regulating metabolism and energy expenditure. By activating this protein, SR9009 can increase the metabolic rate and enhance endurance. This makes it particularly appealing to athletes and fitness enthusiasts looking to improve their performance and stamina during workouts.(4)

Additionally, SR9009 has shown promise in regulating the body's circadian rhythm. This can be beneficial for individuals who struggle with sleep issues or irregular sleep patterns. By optimizing the circadian rhythm, SR9009 also has a positive impact on overall health and well-being.

SR9009, or Stenabolic, is a research chemical that acts as a Rev-ErbA agonist. Its properties include activating the metabolism, improving endurance, and potentially regulating the circadian rhythm. These features make it a fascinating compound for those interested in exercise enhancement and overall fitness.

Overview of SR9011

SR9011 is another compound that falls into the category of Rev-ErbA agonists, just like SR9009. It is sometimes referred to as a "cousin" of SR9009, as it shares similar properties and mechanisms of action.(5) Like SR9009, SR9011 is a research chemical that is being studied for its potential benefits in various areas, including metabolism, endurance, circadian rhythm regulation, and muscle growth.

SR9011 is a synthetic compound that activates the Rev-ErbA proteins in the body, which play a role in regulating gene expression. It is designed to offer similar effects as SR9009 but with some differences in terms of its chemical structure.

SR9011 works by binding to the Rev-ErbA proteins in the body and influencing their activity levels. These proteins are involved in regulating various metabolic processes, including energy expenditure and lipid metabolism. By modulating the activity of Rev-ErbA proteins,(6) SR9011 helps to enhance the metabolism and improve overall endurance.

Due to its influence on metabolism and endurance, SR9011 has potential applications in various areas. It may be beneficial for individuals looking to improve their athletic performance, as it could enhance endurance levels. Additionally, SR9011 might have implications in muscle growth, as it may contribute to the regulation of genes involved in muscle development.

Overall, SR9011 is a research chemical that shows promise in various areas related to metabolism, endurance, circadian rhythm, and muscle growth. Further research is needed to fully understand its effects and potential applications in these areas.

SR9009 vs. SR9011 Effects and Benefits

SR9009 and SR9011 are synthetic compounds known as REV-ERB agonists, which have been found to have various effects and benefits on the body. 

It is important to note that scientific research on these compounds is ongoing, and their effects and benefits vary from person to person. Additionally, proper dosing and usage guidelines should be followed to ensure safety.

SR9009 Effects and Benefits

SR9009, also known as Stenabolic, is a Rev-ErbA agonist and falls under the category of research chemicals. This compound has gained attention for its potential effects and benefits. Here are the specific effects and benefits of SR9009:

  • Improved Endurance: SR9009 has been shown to enhance endurance by increasing the number of mitochondria in muscle cells. This leads to improved energy production, allowing individuals to push through intense workouts and training sessions.
  • Faster Metabolism: SR9009 aids in fat loss by boosting metabolism. It increases the metabolic rate, enabling the body to burn calories more efficiently. This is beneficial for individuals looking to shed excess body fat.
  • Better Sleep: Some users report improved sleep quality when taking SR9009. This could be attributed to its impact on circadian rhythm regulation, which helps maintain a healthy sleep-wake cycle.
  • Anti-inflammatory: SR9009 has shown promise as an anti-inflammatory compound. It may help reduce inflammation in the body, which can be beneficial for individuals dealing with chronic inflammation or injuries. This also helps to speed up post-workout recovery times after an intense workout.

SR9011 Effects and Benefits

SR9011 is a research chemical that falls under the category of Rev-ErbA agonists, similar to SR9009. This compound has gained attention for its potential effects on muscle growth, fat loss, improved sleep, and anti-inflammatory properties. Here are the specific effects and benefits associated with SR9011:

  • Muscle Mass Gains: SR9011 is believed to enhance muscle growth by increasing the expression of genes involved in muscle protein synthesis. This leads to improved muscle recovery and growth.
  • Improved Metabolic Rate: SR9011 has thermogenic effects, stimulating the metabolism and promoting fat burning. This helps individuals achieve a leaner physique and reduce body fat.
  • Improved Sleep Quality: Some studies suggest that SR9011 regulates the sleep-wake cycle, leading to better quality sleep. This contributes to improved recovery, hormone regulation, and overall well-being.
  • Anti-inflammatory: SR9011 has shown potential anti-inflammatory effects in animal studies. This is beneficial for individuals dealing with inflammation-related conditions, such as joint pain or autoimmune disorders.

SR9009 vs. SR9011 Side Effects

SR9009 and SR9011 are both research chemicals that are known as Rev-ErbA agonists. They have similar properties and mechanisms of action, but there are some differences in their potential side effects.

In terms of side effects, both SR9009 and SR9011 have been reported to potentially cause liver toxicity. It is important to note that these compounds have not been extensively studied in humans, so the full extent of their potential side effects is not yet known. However, based on animal studies, liver toxicity has been observed with both compounds.

Another potential side effect of both SR9009 and SR9011 is insomnia. These compounds are known to affect the circadian rhythm, and this sometimes leads to difficulty sleeping. It is recommended to take these compounds earlier in the day to minimize the impact on sleep.

Anxiety is another potential side effect that has been reported with the use of both SR9009 and SR9011. These compounds can have an impact on the central nervous system, which may lead to increased anxiety in some individuals. If you have a history of anxiety or other mental health conditions, it is important to consult with a healthcare professional before using these compounds.

It is worth noting that the reported side effects of SR9009 and SR9011 are based on limited research and anecdotal evidence. As such, it is important to approach the use of these compounds with caution and take appropriate precautions.

SR9011 vs. SR9009 Bodybuilding Results

SR9011 and SR9009 are two research chemicals that are believed to have potential benefits for bodybuilders. Both compounds belong to a class of drugs known as Rev-ErbA agonists and are thought to affect metabolism, endurance, and muscle growth.

In terms of bodybuilding results, SR9011 and SR9009 may offer some similar benefits, but there are also differences in their effects on muscle growth, fat loss, and performance:

  • Muscle Growth: SR9011 has been shown to have a significant effect on muscle growth. It is believed to increase the production of proteins that are essential for muscle development, resulting in enhanced muscle mass and strength. On the other hand, SR9009 may also contribute to muscle growth, but to a lesser extent.
  • Fat Loss: Both SR9011 and SR9009 have the potential to aid in fat loss. They are thought to increase the metabolism of fats, allowing for more efficient utilization of stored fat as fuel during workouts. This can lead to a reduction in overall body fat percentage, resulting in a leaner physique.
  • Endurance: SR9011 is known for its ability to improve endurance. It is believed to enhance the body's oxygen utilization and energy production, leading to increased stamina during workouts. SR9009 also has similar effects on endurance and may help athletes push through intense training sessions.
  • Strength: While both compounds can contribute to increased strength, SR9011 is often considered more effective. It is believed to enhance muscle fiber recruitment, leading to greater power output and improved strength gains. SR9009 also has positive effects on strength but to a lesser extent compared to SR9011.

Similarities and Differences Between SR9009 and SR9011

SR9009 and SR9011 are both Rev-ErbA agonists and have similar properties, but they also have some key differences in terms of their effects, benefits, side effects, and applications:


  • Both compounds are research chemicals commonly referred to as Stenabolic.
  • They both function as Rev-ErbA agonists, which means they regulate the body's circadian rhythm and metabolism.
  • Both SR9009 and SR9011 have the potential to enhance endurance and improve athletic performance.
  • They both contribute to fat loss and improved sleep.
  • Both compounds have anti-inflammatory properties.


  • SR9009 is primarily known for its effects on metabolism and endurance. It works by increasing the number of mitochondria in muscle cells, which enhances the body's ability to burn fat and produce energy. SR9009 also regulates the circadian rhythm, leading to better sleep patterns.
  • SR9011 has a stronger focus on muscle growth. It activates genes that are involved in muscle development and protein synthesis, making it a popular choice for those looking to gain muscle mass.
  • SR9009 has been associated with potential liver toxicity, so caution should be taken when using this compound. SR9011 does not have the same reported risks.
  • SR9009 is often used by endurance athletes and those seeking better fat burning capabilities. SR9011 is more commonly used by bodybuilders and individuals looking to increase muscle mass.

In summary, SR9009 and SR9011 are similar in that they are both Rev-ErbA agonists with potential benefits for endurance, fat loss, improved sleep, and anti-inflammation. However, SR9009 is different in how it primarily focuses on improving metabolism and endurance, while SR9011 is more geared towards muscle growth. 


In conclusion, the comparison between SR9009 and SR9011 reveals some important key points to consider. Both compounds, also known as Stenabolic and Rev-ErbA agonists, have distinct properties and potential applications. SR9009 primarily focuses on improving metabolism, endurance, and circadian rhythm, making it a suitable option for individuals looking to enhance physical performance and fat loss. On the other hand, SR9011 is more targeted towards muscle growth, while still offering benefits in terms of fat loss and improved sleep.

When it comes to potential side effects, both compounds may carry risks such as liver toxicity, insomnia, and anxiety. It's important to take precautions and consult with a healthcare professional before using either of these research chemicals.

In terms of bodybuilding results, SR9009 and SR9011 can both contribute to muscle growth, fat loss, endurance, and strength. However, there may be some differences in their effects, with SR9009 being more focused on endurance and fat loss, while SR9011 prioritizes muscle growth.

Overall, both SR9009 and SR9011 are intriguing options for individuals looking to enhance their exercise performance and achieve specific fitness goals. The choice between the two will depend on individual preferences and needs. It is recommended to research each compound, consult with a healthcare professional, and take appropriate measures to ensure safe usage.


Can SR9009 and SR9011 be used for bodybuilding?

Yes, both compounds have the potential to aid in bodybuilding goals by enhancing endurance, promoting fat loss, and potentially supporting muscle growth. However, it is important to remember that these compounds are research chemicals and should be used with caution.

How should SR9009 and SR9011 be used?

The dosages and usage instructions for these compounds may vary. It is recommended to follow the specific guidelines provided by the manufacturer or consult with a healthcare professional for personalized advice.

Are there any legal restrictions on SR9009 and SR9011?

As research chemicals, the legal status of SR9009 and SR9011 SARMs vary by country and jurisdiction. It is important to adhere to local laws and regulations regarding the purchase, possession, and use of these compounds.

Can SR9009 and SR9011 be used by anyone?

It is generally recommended to consult with a healthcare professional before using these compounds, especially if you have any underlying medical conditions or are taking other medications. These compounds are not intended for use by individuals under the age of 18 or by pregnant or breastfeeding women.

Can I stack SR9009 and SR9011 together for better results?

While some users report stacking SR9009 and SR9011 together for enhanced results, it is important to remember that these substances are research chemicals. Their combined effects and safety profile have not been thoroughly studied, and they a higher potential for liver toxicity or cardiovascular issues if used together.

What are the best sources to purchase SR9009 and SR9011?

These substances are often sold online by research chemical suppliers. However, it's crucial to ensure the supplier is reputable, as the quality and purity of these substances can vary. Always perform your due diligence before purchasing.

  1. Stujanna, Endin Nokik et al. “Rev-erb agonist improves adverse cardiac remodeling and survival in myocardial infarction through an anti-inflammatory mechanism.” PloS one vol. 12,12 e0189330. 12 Dec. 2017, doi:10.1371/journal.pone.0189330
  2. Reddy, Sujana, et al. “Physiology, Circadian Rhythm.” StatPearls, StatPearls Publishing, 1 May 2023.
  3. Sánchez López de Nava, Arturo. and Avais Raja. “Physiology, Metabolism.” StatPearls, StatPearls Publishing, 12 September 2022.
  4. Reitz, Cristine J et al. “SR9009 administered for one day after myocardial ischemia-reperfusion prevents heart failure in mice by targeting the cardiac inflammasome.” Communications biology vol. 2 353. 3 Oct. 2019, doi:10.1038/s42003-019-0595-z
  5. Wolff, Samantha E C et al. “The Effect of Rev-erbα Agonist SR9011 on the Immune Response and Cell Metabolism of Microglia.” Frontiers in immunology vol. 11 550145. 25 Sep. 2020, doi:10.3389/fimmu.2020.550145
  6. Cho, Han et al. “Regulation of circadian behaviour and metabolism by REV-ERB-α and REV-ERB-β.” Nature vol. 485,7396 123-7. 29 Mar. 2012, doi:10.1038/nature11048
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