Andarine S4 SARM Review: Benefits, Dosage, & Side Effects

In this Andarine S4 review, you’ll find how it differs from other conventional steroids in the market and why it’s considered safe and potent at the same time.

Do you often hear about the negative side effects of anabolic steroids despite their incredible results when it comes to body transformation?

Have you ever wished to find a safer alternative to traditional steroids?

Well, fret not!

So, what’s the problem with anabolic steroids?

One reason why it is highly problematic is that it affects all sorts of tissues in the body.

They affect muscles and bone density, as well as organs and delicate tissues.

These roids put a lot of pressure on the body and can cause liver damage, heart damage, and an increased chance of liver cancer.

However, there is another class of anabolic-androgenic steroids, called Selective Androgen Receptor Modulators, or SARMs, which specifically target androgen receptors in muscle and bone tissue.

This feature means that with some of the top SARMs you get the same benefits as traditional steroids, but you will have milder side effects.

One of the strongest and most effective SARMs on the market is Andarine, also known by its compound designation of S4 [R].

Selective Androgen Receptor Modulator was first developed to treat muscle wasting diseases and have subsequently been taken up by the bodybuilding and athletic communities as an alternative to traditional roids that also burns body fat.

They're usually not for sale in stores, but anybody with the right connections can get a hold of them (read on to find out where to get them).

SARMs injection into muscle

If you've never heard of Andarine or the other androgen receptor modulator SARM such as SR9009, and you're skeptical about the claims people make regarding this product, this guide is for you.

We'll discuss how S4 works, the benefits and side effects of the compound, as well as whether or not you should include it in your next cycle.

What Is Andarine (S4 SARM)?

Andarine, also known as S-4, was first developed by GTx Inc., a pharmaceutical lab based in Memphis to treat benign prostatic hypertrophy (or enlarged prostate) [R].

Despite not being the most effective SARM on paper (that would be the YK11 SARM), it was rapidly adopted by bodybuilders due to its positive effects and fast results on muscle mass gain and fat loss.

S-4 Andarine

Researchers abandoned S4 during clinical trials due to its lack of effectiveness in treating enlarged prostates.

But many people still use it as an alternative to traditional roids.

NameAndarine (S-4)
EffectsIncreases lean muscle mass
Potential Side EffectsHormone suppression, vision
Half-Life8 hours
Common Dosage50 mg daily
Content50 mg / ml x 50 ml
Money Back GuaranteeCase-by-case
Rating⭐⭐⭐⭐⭐ 4.5/5
Best VendorClick Here ›

However, there are some characteristics that researchers recorded that suggest it may be one of the best SARMs for cutting, bodybuilding, and strength training.

It's highly bioavailable, and it has a long half-life, so you only need to take one pill per day.

How Does It Work?

It works in a similar way to other roids. Many cells in your body contain androgenic receptors that bind to androgens like testosterone.

Once an androgen is bound to the androgen receptor, this sends a signal to the cell that it should boost protein synthesis and start anabolic processes.

What Sets Andarine Apart from Steroids?

What sets this and the other androgen receptor modulators apart is that it's a selective androgen receptor modulator.

This feature means it doesn't target cells indiscriminately as testosterone will. Instead, it focuses on building muscle and bone tissues, telling them to grow and multiply, and prevent muscle wasting.

It doesn't do the same to sex tissues, which is one of the main problems with an overabundance of testosterone.

It will also bind to receptors in the eyes, which leads to a very characteristic side effect that we'll discuss below.

S4 also doesn't get broken down into estrogen or DHT (dihydrotestosterone), so it has a much milder impact on your body in general.

Who Should Take It?

S-4 offers several benefits that many bodybuilders and other athletes can enjoy.

It promotes the rapid growth of lean muscle mass and aids in fat loss. It limits the amount of muscle wasting you encounter during a cut.

And it works fast.

Man with muscles
Man wi

However, as with all other performance-enhancing substances, it's vital to note that S-4 is not a replacement for a good diet and exercise.

Instead, we recommend S4 for people who have hit a plateau in their training and in search of solutions to break through it.

S4 isn't a miracle drug that will give you a ripped body while you sit on the couch and eat chips; you still have to work for your results.

It just makes the results slightly easier to achieve.

People Who Shouldn't Take S-4

That said, Andarine shouldn't be taken by people who are pregnant or breastfeeding. People who have a hormonal imbalance or an overabundance of testosterone should also not take it.

It's always a good idea to discuss your supplement use with an open-minded doctor. A supportive doctor will give you good advice on whether or not it is a reasonable option for you.

Andarine S4 Review: The Benefits

One of the main benefits of S4 SARM is that it's extremely potent at low doses. It has strong growth-promoting effects, meaning you'll find it easier to put on lean muscle mass. You'll also probably find that you recover from your workouts faster.

You can hit the gym much more often and have more intense workouts while on an S4 Andarine cycle. And since you can work out harder and stronger, you'll gain strength faster than ever before, especially when you stack it with other SARMs compounds, like LGD-4033.

Many users who have experience working with S4 SARM say that they don't experience any water retention or bloating when using it. The product is perfect for people who are a couple of weeks out of competition and in search of ways to eliminate water weight.

Dosage & How to Use It

Andarine can be used no matter whether you're bulking, cutting, strength training, or recomping as long as you take the right dose.

In general, you can use it alone at 50 mg/day, and you should notice a boost in the gym.

If you're looking to push the boundaries, it also works great paired with another SARM S4.


Many users tend to combine 50 mg Andarine with 10 mg RAD140 during a bulk.


Surprisingly, S4 works well on a cut. You can pair 25 mg/day dose of Andarine with 20 mg Cardarine during a cut to retain your existing muscle mass, prevent muscle wasting and burn large amounts of fat.


If you're looking to push ever-larger numbers at the gym, you can pair 50 mg/day of Andarine with 10 mg/day of LGD-4033.

This combination has the best effects and works best when chasing strength gains.


If you're looking to gain lean muscle while experiencing a fat loss with the elusive recomp, you can pair this S4 SARM with 25 mg/day Ostarine and 20 mg/day of Cardarine.

These three SARMs together in a stack is so potent, it will give you the ability to work out for many weeks and gain muscle mass despite running on a caloric deficit.

Taking Andarine

Andarine usually comes either in the form of pills with a specified dosage or as a liquid.

Taking the pills is easy, and most people will take their S4 SARM during the morning before breakfast.

If you're using the liquid, you can measure out your desired amount and place it under your tongue.

It will get rapidly absorbed and start working almost immediately.


If you've never tried it before, it may be a good idea to start with a relatively low S4 SARM dosage and slowly increase the dose.


S-4 does come with side effects.


Did you know that you have androgen receptors in your eyes and that one of the effects of Andarine is to target those receptors?

Many users have reported that they get a yellow tint to their vision as a result of using S4.

According to some reviews, you'll notice this when moving into differently-lit rooms or when you drive at night.

This side effect doesn't happen to all users, and it does appear to be dependent on the dosage. It's one of the reasons why it's a good idea to start with a lower dose and work your way up to the desired 50 mg/day sweet spot.

Luckily this side effect isn't permanent, and most users report that their vision returns to normal after stopping for a couple of days.

Hormone Suppression

Even though S4 SARM is much milder and more selective than other stronger androgenic roids, it has hormone-suppressive effects.

It's a good idea to have time to do a mini-PCT (post-cycle therapy) once you've finished your cycle of S4 to get your body back into balance.

It's good practice to do this with any type of SARM compounds, whether you're using it as part of an Andarine stack or on its own.

Many users report that they don't need a full PCT cycle and that their natural testosterone levels increase within four to eight weeks of PCT.

Frequently Asked Questions (FAQs)

Let's look into the most common questions about Andarine S4, SARMS.

Is Andarine S4 legal?

Yes, it is legal to possess Andarine S4 in most countries. However, it is important to note that SARMs are not approved for human consumption by the FDA and other health regulatory agencies.

Can women take Andarine S4?

Yes, women can take Andarine S4. However, it is important to note that it can cause hormonal imbalances in women and lead to unwanted side effects such as deepening of the voice and excessive hair growth.

How long does Andarine S4 stay in your system?

Andarine S4 has a half-life of approximately 4-6 hours [R]. This means that it will take about 24-36 hours for it to completely leave your system.


If you're sick of the side effects of traditional anabolic steroids, SARMs represent a great alternative. They're also not strictly illegal, which makes them safer to get and to use than traditional roids.

S4 is an excellent choice since it can increase muscle mass due to its targeting of selective receptors without a subsequent increase in water retention. It works great in a stack with another SARMs compound like LGD-4033, depending on your needs.

However, you may find that finding sites that offer Andarine on sale is becoming ever more difficult. A lot of these sites are being shut down by the US government.

So, if you do happen to find a batch of S4 on sale, be sure to pick it up as quickly as possible and enjoy the effects of Andarine while you can.

Andarine S-4
Andarine S4 SARM Review: Benefits, Dosage, & Side Effects 1

Looking at trying Andarine S4 (S-4)? Learn more about this selective androgen receptor modulator and its benefits, dosage, and side effects in our review.

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