YK-11 vs RAD-140: Which is the Best SARM?

YK-11 vs RAD-140: Everything you need to know

SARMs have gained popularity in the fitness community for their ability to enhance muscle growth and performance.

Two of the most talked-about SARMs are YK-11 and RAD-140. But which one is truly the best? In this blog post, we will explore the factual data and scientific evidence to compare the benefits and effectiveness of YK-11 vs. RAD-140. 

Whether you're looking to improve your physique or enhance your athletic performance, this article will provide you with the information you need to make an informed decision. Let's dive in and find out which SARM reigns supreme.

Introduction to YK-11 and RAD-140

YK-11 and RAD-140 are both selective androgen receptor modulators (SARMs)(1) that have gained popularity in the fitness industry for their potential muscle-building and bodybuilding benefits.

Both YK-11 and RAD-140 offer promising benefits for those looking to enhance their muscle growth and bodybuilding results.

Overview of YK-11

YK-11 is a selective androgen receptor modulator (SARM) known for its unique characteristics and potential benefits in the fitness industry. It functions as a myostatin inhibitor,(2) which means it helps inhibit the production of myostatin, a protein that limits muscle growth. By doing so, YK-11 may promote enhanced muscle mass and strength gains.

YK-11 has the potential to support significant muscle growth due to its myostatin inhibiting properties. Users may experience improved strength and power output, leading to enhanced athletic performance. 

YK-11 has been suggested to have positive effects on bone health and density, potentially reducing the risk of fractures and injuries. As a SARM, YK-11 is believed to have a lower risk of unwanted side effects compared to traditional steroids.

It's important to note that further research is still needed to fully understand the long-term effects and potential risks associated with YK-11.

Overview of RAD-140

RAD-140, also known as Testolone, is a selective androgen receptor modulator (SARM) that has gained popularity in the fitness industry for its potential benefits. It is specifically designed to target androgen receptors in the muscle and bone tissues, leading to increased muscle growth and bone strength.

One of the main advantages of RAD-140 is its ability to promote lean muscle mass development. It works by binding to the androgen receptors in the muscles and increasing protein synthesis, which ultimately results in enhanced muscle growth. This makes RAD-140 a desirable compound for individuals looking to build quality muscle while minimizing unwanted fat gains.

Additionally, RAD-140 has been shown to have potential fat-burning effects. It stimulates the breakdown of fat cells and enhances the body's metabolism, leading to increased fat loss. This can be especially beneficial for individuals aiming to achieve a lean and shredded physique.

Apart from its muscle-building and fat-burning properties, RAD-140 is also believed to possess neuroprotective effects. It has been shown to protect brain cells from damage and promote overall brain health.(3) This makes it an interesting compound for individuals seeking cognitive enhancement and mental clarity.

Overall, RAD-140 offers a range of potential benefits for individuals interested in bodybuilding and fitness. Its ability to promote lean muscle growth, burn fat, and support brain health makes it a versatile compound for those looking to enhance their physique and overall well-being.

YK-11 vs. RAD-140 Effects and Benefits

When comparing the effects and benefits of YK-11 and RAD-140, both compounds have their unique properties and advantages for the bodybuilding community.

It's important to note that both compounds are selective androgen receptor modulators (SARMs), designed to target specific tissues while minimizing side effects on other organs. While YK-11 focuses on myostatin inhibition and bone health, RAD-140 is more renowned for its effects on lean muscle growth and fat loss. 

YK-11 Effects and Benefits

YK-11 is a potent selective androgen receptor modulator (SARM) that offers several effects and benefits in the realm of bodybuilding and fitness. One of its key characteristics is its ability to inhibit myostatin, which is a protein that limits muscle growth. 

By inhibiting myostatin, YK-11 promotes muscle mass increase and can result in significant gains in strength. Additionally, YK-11 has been shown to enhance bone health, making it a popular choice among athletes and bodybuilders.

Here is a brief summary of YK-11's bennefits for fitness enthusiasts:

  • Muscle Mass Increase: YK-11 promotes muscle growth by inhibiting myostatin, allowing for greater muscle development and size.
  • Bone Health: YK-11 has shown potential in supporting bone health and strength, which can be particularly beneficial for individuals involved in high-impact activities.
  • Strength Gains: Users of YK-11 often report significant increases in strength, leading to improved performance in the gym and increased power output.
  • Improved Recovery: YK-11 aids in faster recovery after intense workouts, allowing for more frequent and effective training sessions.
  • Minimal Side Effects: Compared to traditional anabolic steroids, YK-11 is considered to have minimal side effects, making it a preferable option for many fitness enthusiasts.

It's important to note that individual experiences vary, and it's advisable to consult with a healthcare professional or fitness expert before starting any supplementation regimen.

RAD-140 Effects and Benefits

RAD-140, also known as Testolone, is a powerful selective androgen receptor modulator (SARM) known for its ability to promote lean muscle growth, increase strength, and aid in fat loss.

Here are some of the key effects and benefits of RAD-140:

  • Lean Muscle Growth: RAD-140 is highly effective at promoting muscle growth by binding to androgen receptors in the body. It stimulates protein synthesis, leading to an increase in lean muscle mass.
  • Fat Loss: RAD-140 helps in reducing body fat by increasing the body's basal metabolic rate (BMR). It promotes the breakdown of stored fat and enhances the body's ability to utilize fat as energy.
  • Neuroprotection: RAD-140 has shown neuroprotective effects, which means it can help protect and maintain brain health. It may have potential use in treating neurodegenerative diseases such as Alzheimer's.
  • Endurance and Stamina: RAD-140 improves endurance and stamina, allowing users to engage in longer and more intense workouts without experiencing fatigue.
  • Improved Recovery Time: RAD-140 aids in faster recovery after intense workouts by reducing muscle damage and inflammation. It helps preserve muscle tissue and promotes quicker healing and repair.

YK-11 vs. RAD-140 Side Effects

When comparing the potential side effects of YK-11 and RAD-140, it's important to note that both compounds are selective androgen receptor modulators (SARMs) and have the potential to affect hormone levels within the body.

Here are some of the potential side effects associated with each compound:

YK-11:

  • Testosterone Suppression: YK-11 has the potential to suppress natural testosterone levels in your body, which can lead to decreased libido, fatigue, and potential muscle loss after discontinuation.
  • Liver Toxicity: There is limited research available on the liver toxicity of YK-11, but some studies suggest that it may have hepatotoxic effects.
  • Hair Loss: Some users have reported hair loss while using YK-11. This side effect may be more prevalent in individuals who are genetically predisposed to male pattern baldness.
  • Acne: YK-11 potentially stimulates sebum production, leading to an increased risk of acne breakouts.
  • Mood Changes: Some users have reported mood swings and irritability while using YK-11.

RAD-140:

  • Testosterone Suppression: RAD-140 is potentially a testosterone suppressive, similar to YK-11. It is recommended to use a post-cycle therapy (PCT) supplement after a RAD-140 cycle in order to re-regulate testosterone production. 
  • Liver Toxicity: There is limited evidence to suggest that RAD-140 has liver toxic effects, but further research is needed to fully understand its impact.
  • Hair Loss: Like YK-11, RAD-140 may also contribute to hair loss in individuals who are genetically predisposed to male pattern baldness.
  • Acne: RAD-140 has the potential to increase sebum production, leading to an increased risk of acne breakouts.
  • Mood Changes: Some users have reported mood swings and irritability while using RAD-140.

It's important to note that individual experiences with side effects vary, and proper dosage and cycle length play a role in minimizing these effects. 

RAD-140 vs. YK-11 Bodybuilding Results

When comparing the bodybuilding results of RAD-140 and YK-11, it is important to understand that both compounds are highly regarded for their muscle-building properties. Here is a comparison of the potential benefits one can expect from each:

RAD-140:

  • Lean Muscle Growth: RAD-140 is known for its ability to increase muscle mass without the water retention often associated with other compounds. It also provides stronger and more powerful muscle tissue, without the negative side effects of anabolic steroids.
  • Fat Loss: RAD-140 helps to increase fat oxidation, leading to a leaner and more shredded physique.
  • Increased Vascularity: Users often report improved vascularity, and a more defined appearance while using RAD-140.
  • Enhanced Strength Gains: RAD-140 is renowned for its ability to significantly increase strength levels, allowing users to lift heavier weights and maximize their training potential.
  • Improved Recovery Time: RAD-140 can help to speed up recovery between workouts, reducing muscle soreness and allowing for more frequent and intense training sessions.

YK-11:

  • Builds Muscle Mass: YK-11 is known for its potent muscle-building properties, with users often reporting rapid gains in muscle size and strength.
  • Increased Strength: YK-11 helps to enhance strength levels, allowing users to push through plateaus and achieve new personal records.
  • Fat Loss: YK-11 may also contribute to some fat loss, although it is not as pronounced as with RAD-140.
  • Bone Health: YK-11 has been shown to have positive effects on bone health, which can be beneficial for overall strength and durability.

It is important to note that individual results vary, and the outcomes will depend on factors such as dosage, diet, exercise, and genetics.

Similarities and Differences Between YK-11 and RAD-140

Both YK-11 and RAD-140 are SARMs (selective androgen receptor modulators) that are commonly used in the fitness industry for their muscle-building and bodybuilding benefits. However, there are some notable differences between these two compounds:

Similarities:

  • Both compounds are designed to target and activate androgen receptors in the body, leading to increased muscle growth and strength gains.
  • They both help in reducing body fat, improving endurance, and enhancing recovery time.
  • YK-11 and RAD-140 are known for their ability to improve bone health and density.

Differences:

  • When it comes to each supplement's half-life (reaction time), YK-11 is fast-acting with a half-life of 10-12 hours. However, RAD-140 has a slower half-life, with effects taking place after 20-24 hours.
  • YK-11 is unique as it acts as a myostatin inhibitor, which means it prevents the production of a protein that limits muscle growth. RAD-140, on the other hand, primarily focuses on promoting lean muscle growth.
  • YK-11 has shown potential benefits in improving bone health, which RAD-140 does not specifically target.
  • RAD-140 is known to have neuroprotective effects, which may be beneficial for athletes in terms of brain health and function.
  • YK-11 may have a higher risk of testosterone suppression compared to RAD-140.
  • YK-11 may have a higher risk of liver toxicity and potential hair loss, while RAD-140 may have a higher risk of acne and mood changes.

It is important to note that the overall effects and side effects of these compounds can vary depending on factors such as dosage, individual response, and adherence to proper usage guidelines. 

Final Verdict

When it comes to choosing between YK-11 and RAD-140, the decision ultimately depends on your individual fitness goals and preferences. Here are some key points to consider:

Ultimately, the choice between YK-11 and RAD-140 depends on your personal fitness goals. If you are looking for significant muscle mass increase and size, YK-11 might be the better option. 

On the other hand, if you want to focus on lean muscle development and fat loss, RAD-140 is one of the best SARMs for massive muscle growth.

Always remember to do thorough research, consult with a healthcare professional, and follow proper dosage instructions for optimal results and safety.

FAQs

Are YK-11 and RAD-140 legal?

The legal status of YK-11 and RAD-140 varies from country to country. In some jurisdictions, they are classified as research chemicals and not intended for human consumption. It is important to familiarize yourself with the laws in your specific region before purchasing or using these substances.

Do YK-11 and RAD-140 require a prescription?

As selective androgen receptor modulators (SARMs), YK-11 and RAD-140 are not approved for medical use by regulatory authorities. Therefore, they cannot be legally prescribed by healthcare professionals. They are often consumed for research purposes or as dietary supplements.

What are the recommended dosages for YK-11 and RAD-140?

The recommended dosages for YK-11 and RAD-140 depending on factors such as individual tolerance, fitness goals, and experience level. Typically, the advised dosage for your YK11 cycle is 10 to 30 mg daily, cycled for 4 to 8 weeks. However, a RAD-140 cycle requires a daily dose of 10mg. It is advised to start with low dosages and gradually increase as needed. Consulting with a healthcare professional or experienced fitness expert is recommended for personalized guidance.

Can women use YK-11 and RAD-140?

Due to their potential virializing effects, YK-11 and RAD-140 are generally not recommended for use by women. These compounds have the potential to disrupt hormonal balance and may lead to unwanted side effects. Women should consult with their healthcare provider before considering the use of SARMs.

Are there any recommended cycle lengths for YK-11 and RAD-140?

A  YK11 cycle is typically 4-8 weeks, whilst a RAD 140 cycle is typically range from 8 to 12 weeks. It is important to follow recommended cycle lengths and include post-cycle therapy (PCT) to help restore natural hormone levels. PCT protocols may vary, so seeking guidance from a qualified professional is essential.

Can YK-11 and RAD-140 be stacked with other supplements?

YK-11 and RAD-140 can be stacked with other supplements to maximize results. However, it is important to carefully research potential interactions and consult with a healthcare professional before stacking these two SARMs for muscle growth in your body.

How do I choose between natural legal steroids and SARMs?

Natural steroids are legal and safe, however they do not have the same impact that SARMs provides when dosed correctly and followed by a fitness regimen. Many bodybuilders prefer SARMs due to their fast-acting nature. The choice between the two depends on your goals and tolerance. Speak with a healthcare professional if you want to add a new supplement to your workout routine in order to decide which one will suit your lifestyle the best and improve anabolic activity in your body. 

Does YK-11 only come in the form of a pill?

No, however this is the most popular method of administration. For those that want them, muscle injections are an option. They must be administered under medical supervision, and must be taken with a healthy diet for the best results. It's important to remember that YK-11 is not FDA-approved, so finding the correct method of administration and dosage must be done with the guidance of a medical professional.


References
  1. Rosen, J, and A Negro-Vilar. “Novel, non-steroidal, selective androgen receptor modulators (SARMs) with anabolic activity in bone and muscle and improved safety profile.” Journal of musculoskeletal & neuronal interactions vol. 2,3 (2002): 222-4. ()
  2. Lee, Su Jin et al. “Myostatin inhibitor YK11 as a preventative health supplement for bacterial sepsis.” Biochemical and biophysical research communications vol. 543 (2021): 1-7. doi:10.1016/j.bbrc.2021.01.030 ()
  3. Jayaraman, Anusha et al. “Selective androgen receptor modulator RAD140 is neuroprotective in cultured neurons and kainate-lesioned male rats.” Endocrinology vol. 155,4 (2014): 1398-406. doi:10.1210/en.2013-1725 ()
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